Under the background of the new liberal arts, cultivating the innovation and entrepreneurship abilities of talents majoring in fashion and costume design in colleges and universities has become extremely crucial. Cultivating such abilities is an important way to improve the quality of talent cultivation in art and design majors at universities, which can promote the enhancement of students' practical skills and the progress of their creative capabilities. The significance of cultivating innovation and entrepreneurship abilities is largely reflected in overall disciplinary education. If the cultivation effect of students' innovation and entrepreneurship abilities cannot be ensured, or if the strategies and methods used in basic courses are relatively backward and remain stagnant for a long time, it is easy to cause disconnections when integrating with professional courses. Through investigations and practical explorations, it has been found that many colleges and universities have adjusted their art and design professional courses, but innovation and entrepreneurship education courses account for a relatively small proportion and are easily overlooked. Moreover, with the rapid development of the fashion design industry in recent years, higher requirements have been put forward for the cultivation of innovative and entrepreneurial talents. Exploring new models for cultivating such talents has become the main direction and goal of teaching reforms for fashion and costume design majors in colleges and universities.